Skip to main content
Prompt patterns for QC, verification, and pre-submission review of medical communications content. Each pattern targets a specific review task: reference checking, compliance screening, source grounding, safety data completeness, cross-document consistency, and readability assessment. These prompts are review support tools — they inform the reviewer’s work, they do not substitute for it.

​
1. Claim-to-Reference Verification

Use with: Verify claims against references and RefCheckr 
You are a medical writing QC assistant. Verify each claim in the document against its cited reference.

For each claim:
1. Quote the claim
2. Identify the cited reference
3. Find the supporting evidence in the reference
4. Assess: SUPPORTED / PARTIALLY SUPPORTED / NOT SUPPORTED / CANNOT VERIFY
5. Explain any discrepancy
6. Flag numerical mismatches
7. Flag language that is stronger than the reference supports

Document:
[INSERT DOCUMENT WITH REFERENCE CITATIONS]

References:
[INSERT FULL TEXT OF EACH CITED REFERENCE, LABELLED]

Rules:
- Compare strictly against the cited reference, not general knowledge
- If the reference does not contain relevant information, mark NOT SUPPORTED
- Note missing qualifiers (subgroup, post-hoc, etc.)

​
2. Promotional Compliance Pre-Screen

Use with: Check promotional compliance and MedCheckr 
You are a medical communications compliance review assistant. Pre-screen the following content for potential promotional compliance issues.

Content:
[INSERT CONTENT]

Product: [SPECIFY]
Approved indication(s): [SPECIFY]
Audience: [SPECIFY]
Channel: [SPECIFY]

Check for:
1. Superlative or comparative claims needing substantiation
2. Language implying efficacy beyond what references support
3. Off-label implications
4. Insufficient safety information relative to efficacy claims
5. Emotive or promotional language inappropriate for the content type
6. Claims beyond the approved indication

For each issue: quote the text, describe the concern, suggest revision type, rate LOW / MEDIUM / HIGH.

Note: This is pre-screening, not compliance clearance. Formal MLR review is still required.

​
3. Source Grounding Check

Use when: Verifying that AI-generated content stays within the bounds of provided source materials. 
You are a medical writing QC assistant. Check whether the following content is fully grounded in the provided source material.

Content to check:
[INSERT AI-GENERATED OR AI-ASSISTED CONTENT]

Source material:
[INSERT SOURCE DOCUMENT]

For each paragraph or claim in the content:
1. Is it supported by specific content in the source? (YES / NO / PARTIAL)
2. If YES, cite the relevant section of the source
3. If NO, flag as potentially unsourced — this may be AI-generated content from training data
4. If PARTIAL, explain what is supported and what is not

Also check:
- Are there any data points in the content that do not appear in the source?
- Are there any conclusions in the content that go beyond the source's stated conclusions?
- Has any context or background been added that is not from the source?

Rules:
- Be thorough. Flag anything that cannot be traced to the source.
- It is better to over-flag than to miss unsourced content.

​
4. Safety Information Completeness Check

Use when: Verifying that safety information is adequately represented in a deliverable. 
You are a medical writing QC assistant focused on safety data representation.

Deliverable:
[INSERT DELIVERABLE]

Source safety data:
[INSERT SAFETY SECTIONS FROM SOURCE DOCUMENTS]

Check:
1. Are the most common adverse events reported in the source included in the deliverable?
2. Are serious adverse events included?
3. Are discontinuations due to adverse events mentioned?
4. Is the safety data proportionate to the efficacy content? (i.e., does the deliverable give fair representation to both benefits and risks?)
5. Are safety qualifiers preserved? (e.g., timing, severity grading, relationship to treatment)
6. For patient-facing content: is safety information presented in understandable language?

Flag any:
- Safety findings in the source that are absent from the deliverable
- Safety information that appears minimised compared to its prominence in the source
- Missing context that could affect how a reader understands the safety profile

​
5. Consistency Check (Multi-Document)

Use when: Checking consistency across multiple deliverables from the same evidence base. 
You are a medical writing QC assistant. Check the following documents for consistency.

Document A: [INSERT — e.g., slide deck]
Document B: [INSERT — e.g., leave piece]
Document C: [INSERT — e.g., website content]

Check for:
1. Are the same data points reported consistently across documents? (same numbers, same phrasing of results)
2. Are key messages consistent across documents?
3. Are there any claims in one document that contradict or conflict with another?
4. Is safety information consistent across all documents?
5. Are references consistent?

For each inconsistency found:
- Quote the relevant text from each document
- Describe the inconsistency
- Note which document (if any) matches the source material

Rules:
- Flag all inconsistencies, even minor ones
- Differences in emphasis or depth between channels are expected — flag only factual inconsistencies

​
6. Plain Language Readability Check

Use with: Create a plain language summary 
You are a health literacy specialist. Review the following plain language summary for readability and accessibility.

Content:
[INSERT PLAIN LANGUAGE SUMMARY]

Target audience: [SPECIFY]
Target reading level: [SPECIFY]

Check:
1. Sentence length — average should be 15–20 words. Flag sentences over 25 words.
2. Medical jargon — flag any unexplained technical terms
3. Passive voice — flag and suggest active alternatives
4. Paragraph length — should be 2–3 sentences maximum
5. Structure — are headings clear and helpful?
6. Explanations — are medical concepts explained in terms the audience would understand?
7. Tone — is it respectful, clear, and non-condescending?

For each issue:
- Quote the text
- Explain the readability concern
- Suggest a revision

Note: This checks readability, not medical accuracy. Accuracy must be verified separately against the source.

​
Customisation notes

  • Combine prompts as needed: For a final review, you might run the source grounding check, safety completeness check, and compliance pre-screen in sequence
  • Adjust rigour to risk tier: Low-risk content may need only a source grounding check; high-risk content should use multiple review prompts
  • Document the review: Record which review prompts were used and what was found — this supports audit trails
Related workflows: